pentobarbital will lessen the extent or impact of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or result of linagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Use of other therapies is strongly advised when linagliptin will be to be administered which has a CYP3A4 inducer
Contraindicated (1)pentobarbital will lower the level or effect of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Reserve concomitant prescribing of such drugs in clients for whom other treatment method alternatives are inadequate. Restrict dosages and durations on the least expected. Check closely for indications of respiratory depression and sedation.
pentobarbital will minimize the extent or influence of paclitaxel protein certain by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will lower the level or effect of dasatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will reduce the extent or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Exercise warning any time a barbiturate is administered to the nursing girl; modest amounts of barbiturates are excreted within the milk
pentobarbital will lower the extent or outcome of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. The efficacy of hormonal contraceptives could possibly be lessened.
Remark: Barbiturates may well maximize adverse effects, including respiratory depression, produced by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.
Watch Carefully (1)pentobarbital will lower the level or effect of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to some lower in fentanyl plasma concentrations, insufficient efficacy or, maybe, enhancement of the withdrawal syndrome inside of a patient who's got developed physical dependence to fentanyl. Just after halting a CYP3A4 inducer, as the effects in the inducer drop, the fentanyl plasma focus will raise which could enhance or extend both the therapeutic and adverse effects.
pentobarbital will reduce the level or result of docetaxel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.
pentobarbital will minimize the level or influence of quinidine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lower the extent or outcome of ritonavir by affecting more info hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.